This report examines the U.S. partnership with Senegal to advance women’s and family health, and finds that the United States can play an important role in furthering Senegal’s capacity to sustain its health gains, build its investment case for international financing, and navigate the complex challenges ahead. To consolidate gains, the report argues that the United States should elevate attention and resources for integrated services to improve access to family planning and child health services. In addition, the report highlights the ongoing challenge of maternal mortality, which will require U.S. support to go beyond program-specific funding in order to accelerate efforts to strengthen health systems and human resources for health. Finally, the report calls for the United States to assist Senegal as it develops plans for a gradual, phased transition away from external support to more sustainable financing of health programs through the government of Senegal, the private sector, and new international financing mechanisms.